In the past few years, healthcare practitioners have been hearing a great deal about bovine colostrum, a relatively a new superpower medicine or health supplement intended to optimize the immune systems of both healthy and chronically ill individuals. Testimonials, anecdotal reports, as well as the marketing efforts of several supplement manufacturers and distributors have generated much of the excitement about colostrum. The past 20 years has also witnessed the publication of over 2, 000 research papers that strongly support both colostrum and its numerous components. For me, more than 1 billion satisfied patients’ results of IMMURICH define the ultimate story about colostrums. The purpose of this paper is to review the scientific evidence for the clinical application of a promising immune system modulator. Colostrum, Life's First Food, for me is that bovine colostrum "rebuilds the immune system, destroys viruses, bacteria." ", and fungi, accelerates healing of all body tissue, helps lose weight, burn fat, increase bone and lean muscle mass, and slows down and even reverses aging, " According to Clark and well-known naturopathic physician Dr. Bernard Jensen", colostrum plays a therapeutic role in AIDS, cancer, heart disease, diabetes, autoimmune diseases, allergies, herpes"', bacterial", viral, and parasitic' infections, gingivitis, colds, the flu, and much more. Colostrum has antioxidant and anti-inflammatory properties, and provides many vitamins, minerals, enzymes, and amino acids.